Se presenta un artículo acerca de los factores de riesgo asociados a la dermatitis atópica en niños, enfermedad con una incidencia significativa en el municipio Nuevitas. A partir de la revisión de Historias Clínicas en los Consultorios 4,5 y 6 del territorio, en el período comprendido de enero a septiembre del 2015, se constató como importantes los factores genéticos y los medioambientales en estos pacientes. Con el objetivo de disminuir los últimos se elaboró una estrategia educativa para la familia de (...) los infantes. Se aplicó una encuesta inicial y una final con una población de 60 familias y una muestra de 30 que representa el 50 % con el criterio de inclusión de tener algún o algunos de estos factores. Se concluye que la estrategia contribuyó a transformar los estilos de vida en las familias estudiadas. The article deals with risk factors associated to atopic dermatitis in children, a disease with a significant effect on Nuevitas municipality. Starting from the checking of clinical histories in doctors' offices 4, 5 and 6 in the municipality from January to September 2015, genetic and environmental factors were confirmed to be important. Aiming at lessening these risks, an educational strategy for the children's families was developed. An initial and a final survey of a population of 60 families and a sample of 30, make for a 50 % with inclusion criterion of having some or a lot of these factors. It was reached the conclusion that the strategy contributed to transforming lifestyles in the studied families. (shrink)

Moral para médicos.--Moral para profesores.--Moral para estudiantes de medicina.--Moral para esposas de médicos.

This paper defends an inferential conception of scientific representation. It approaches the notion of representation in a deflationary spirit, and minimally characterizes the concept as it appears in science by means of two necessary conditions: its essential directionality and its capacity to allow surrogate reasoning and inference. The conception is defended by showing that it successfully meets the objections that make its competitors, such as isomorphism and similarity, untenable. In addition the inferential conception captures the objectivity of the cognitive representations (...) used by science, it sheds light on their truth and completeness, and it explains the source of the analogy between scientific and artistic modes of representation. (shrink)

I argue against theories that attempt to reduce scientific representation to similarity or isomorphism. These reductive theories aim to radically naturalize the notion of representation, since they treat scientist's purposes and intentions as non-essential to representation. I distinguish between the means and the constituents of representation, and I argue that similarity and isomorphism are common but not universal means of representation. I then present four other arguments to show that similarity and isomorphism are not the constituents of scientific representation. I (...) finish by looking at the prospects for weakened versions of these theories, and I argue that only those that abandon the aim to radically naturalize scientific representation are likely to be successful. (shrink)

Xenotransplantation is any transplantation, implantation, or infusion of either live cells, tissues, or organs from a nonhuman animal source, or human bodily fluids, cells, tissues, or organs that have had ex vivo contact with live nonhuman animal cells, tissues, or organs into a human recipient. Most scientists agree that clinical xenotransplantation should not be performed in the absence of accompanying public health safeguards The science upon which that consensus is based has been extensively described in the literature. By and large (...) the most compelling reason for public health safeguards is the possible introduction of new infectious agents into the human life cycle as a result of xenotransplantation.The most frequent source of new infectious diseases in human populations is the transfer of agents, such as viruses, bacteria, or prions, from animals to man. Human diseases and infectious agents that are thought to have originated from animals include influenza, rabies, malaria, lassa fever, lyme disease, AIDS, yellow fever, tuberculosis, the human t-cell lymphotropic virus, the herpes B virus, the hantavirus, and even the bubonic and pneumonic plagues. (shrink)

Xenotransplantation is any transplantation, implantation, or infusion of either live cells, tissues, or organs from a nonhuman animal source, or human bodily fluids, cells, tissues, or organs that have had ex vivo contact with live nonhuman animal cells, tissues, or organs into a human recipient. Most scientists agree that clinical xenotransplantation should not be performed in the absence of accompanying public health safeguards The science upon which that consensus is based has been extensively described in the literature. By and large (...) the most compelling reason for public health safeguards is the possible introduction of new infectious agents into the human life cycle as a result of xenotransplantation.The most frequent source of new infectious diseases in human populations is the transfer of agents, such as viruses, bacteria, or prions, from animals to man. Human diseases and infectious agents that are thought to have originated from animals include influenza, rabies, malaria, lassa fever, lyme disease, AIDS, yellow fever, tuberculosis, the human t-cell lymphotropic virus, the herpes B virus, the hantavirus, and even the bubonic and pneumonic plagues. (shrink)

It is shown that the before-before (or Suarez-Scarani) experiment refutes hidden variable models with a deterministic (“realistic”) nonlocal part, whereas experiments violating Leggett-type inequalities refute models with biased random local part. Therefore the claim that Gröblacher et al. (Nature 446:871–875, 2007) present “an experimental test of nonlocal realism” is misleading, and Marek Żukowski’s (Found. Phys. 38:1070, 2008) comment misses the point. A new experiment is suggested.

L'index detaille de la Metaphysique d'Aristote publie en 1597 par Suarez, constitue une introduction aux Disputes metaphysiques. Il a pour objectif de produire les conditions d'un renouvellement de l'heritage de la Metaphysique d'Aristote en redefinissant le contenu et les limites d'une science de l'etant.Le projet de refondation de la metaphysique comme ontologie s'effectue dans cet ouvrage de presentation en quatre moments:1) L'exposition du probleme de la nature de la connaissance qui implique le depassement de l'equivocite de la notion de sagesse.2) (...) La determination de l'objet, des proprietes et des principes veritables de la metaphysique en tant que science de l'universel, c'est a dire de l'etantite de l'etant selon son abstraction la plus extreme.3) La redefinition du statut de la realite a partir d'une theorie de la representation de l'objet qui fasse abstraction de l'objet, c'est a dire qui procede a l'indifferenciation des etants afin d'en donner une representation universelle et abstraite; ainsi est affirme le primat d'une ontologie de l'essence sur toute ontotheologie.4) Enfin, la mise en place d'un systeme de reference transcendantal rendant possible une fondation universelle de la comprehension de l'etant par la mediation d'une theorie du concept.L'index prefigure ainsi, par son ambition et sa demarche, ce que Heidegger nommera, en evoquant la philosophie de Suarez, l'avenement du "caractere fondamental de la metaphysique moderne". (shrink)

This paper expands on, and provides a qualified defence of, Arthur Fine's selective interactions solution to the measurement problem. Fine's approach must be understood against the background of the insolubility proof of the quantum measurement. I first defend the proof as an appropriate formal representation of the quantum measurement problem. The nature of selective interactions, and more generally selections, is then clarified, and three arguments in their favour are offered. First, selections provide the only known solution to the measurement problem (...) that does not relinquish any of the explicit premises of the insolubility proofs. Second, unlike some no-collapse interpretations of quantum mechanics, selections suffer no difficulties with non-ideal measurements. Third, unlike most collapse interpretations, selections can be independently motivated by an appeal to quantum propensities. IntroductionThe problem of quantum measurement2.1 The ignorance interpretation of mixtures2.2 The eigenstate–eigenvalue link2.3 The quantum theory of measurementThe insolubility proof of the quantum measurement3.1 Some notation3.2 The transfer of probability condition (TPC)3.3 The occurrence of outcomes condition (OOC)A defence of the insolubility proof4.1 Stein's critique4.2 Ignorance is not required4.3 The problem of quantum measurement is an idealisationSelections5.1 Representing dispositional properties5.2 Selections solve the measurement problem5.3 Selections and ignoranceNon-ideal selections6.1 No-collapse interpretations and non-ideal measurements6.2 Exact and approximate measurements6.3 Selections for non-ideal interactions6.4 Approximate selections6.5 Implications for ignoranceSelective interactions test quantum propensities7.1 Equivalence classes as physical ‘aspects’: a critique7.2 Quantum dispositions7.3 Selections as a propensity modal interpretation7.4 A comparison with Popper's propensity interpretation. (shrink)

1Department of Philosophy, University of Bristol, 9 Woodland Road, Bristol BS8 1TB, UKScience Without Laws Ronald Giere Chicago, IL University of Chicago Press 1999 x + 285 Hardback£17.50.

Bourrat and Griffiths :33, 2018) have recently argued that most of the evidence presented by holobiont defenders to support the thesis that holobionts are evolutionary individuals is not to the point and is not even adequate to discriminate multispecies evolutionary individuals from other multispecies assemblages that would not be considered evolutionary individuals by most holobiont defenders. They further argue that an adequate criterion to distinguish the two categories is fitness alignment, presenting the notion of fitness boundedness as a criterion that (...) allows divorcing true multispecies evolutionary individuals from other multispecies assemblages and provides an adequate criterion to single out genuine evolutionary multispecies assemblages. A consequence of their criterion is that holobionts, as conventionally defined by hologenome defenders, are not evolutionary individuals except in very rare cases, and for very specific host-symbiont associations. This paper is a critical response to Bourrat and Griffiths’ arguments and a defence of the arguments presented by holobiont defenders. Drawing upon the case of the hologenomic basis of the evolution of sanguivory in vampire bats, I argue that Bourrat and Griffiths overlook some aspects of the biological nature of the microbiome that justifies the thesis that holobionts are evolutionarily different to other multispecies assemblages. I argue that the hologenome theory of evolution should not define the hologenome as a collection of genomes, but as the sum of the host genome plus some traits of the microbiome which together constitute an evolutionary individual, a conception I refer to as the stability of traits conception of the hologenome. Based on that conception I argue that the evidence presented by holobiont defenders is to the point, and supports the thesis that holobionts are evolutionary individuals. In this sense, the paper offers an account of the holobiont that aims to foster a dialogue between hologenome advocates and hologenome critics. (shrink)

Contemporary biological research has suggested that some host–microbiome multispecies systems (referred to as “holobionts”) can in certain circumstances evolve as unique biological individual, thus being a unit of selection in evolution. If this is so, then it is arguably the case that some biological adaptations have evolved at the level of the multispecies system, what we call hologenomic adaptations. However, no research has yet been devoted to investigating their nature, or how these adaptations can be distinguished from adaptations at the (...) species-level (genomic adaptations). In this paper, we cover this gap by investigating the nature of hologenomic adaptations. By drawing on the case of the evolution of sanguivory diet in vampire bats, we argue that a trait constitutes a hologenomic adaptation when its evolution can only be explained if the holobiont is considered the biological individual that manifests this adaptation, while the bacterial taxa that bear the trait are only opportunistic beneficiaries of it. We then use the philosophical notions of emergence and inter-identity to explain the nature of this form of individuality and argue why it is special of holobionts. Overall, our paper illustrates how the use of philosophical concepts can illuminate scientific discussions, in the trend of what has recently been called metaphysics of biology. (shrink)

Symbiosis plays a fundamental role in contemporary biology, as well as in recent thinking in philosophy of biology. The discovery of the importance and universality of symbiotic associations has brought new light to old debates in the field, including issues about the concept of biological individuality. An important aspect of these debates has been the formulation of the hologenome concept of evolution, the notion that holobionts are units of natural selection in evolution. This review examines the philosophical assumptions that underlie (...) recent proposal of the hologenome concept of evolution, and traces those debates back in time to their historical origins, to the moment when the connection between the topics of symbiosis and biological individuality first caught the attention of biologists. The review is divided in two parts. The first part explores the historical origins of the connection between the notion of symbiosis and the concept of biological individuality, and emphasizes the role of A. de Bary, R. Pound, A. Schneider and C. Merezhkowsky in framing the debate. The second part examines the hologenome concept of evolution and explores four parallelisms between contemporary debates and the debates presented in the first part of the essay, arguing that the different debates raised by the hologenome concept were already present in the literature. I suggest that the novelty of the hologenome concept of evolution lies in the wider appreciation of the importance of symbiosis for maintaining life on Earth as we know it. Finally, I conclude by suggesting the importance of exploring the connections among contemporary biology, philosophy of biology and history of biology in order to gain a better understanding of contemporary biology. (shrink)

Abstract: It is often assumed without argument that fictionalism in the philosophy of science contradicts scientific realism. This paper is a critical analysis of this assumption. The kind of fictionalism that is at present discussed in philosophy of science is characterised, and distinguished from fictionalism in other areas. A distinction is then drawn between forms of fictional representation, and two competing accounts of fiction in science are discussed. I then outline explicitly what I take to be the argument for the (...) incompatibility of scientific realism with fictionalism. I argue that some of its premises are unwarranted, and are moreover questionable from a fictionalist perspective. The conclusion is that fictionalism is neutral in the realism-antirealism debate, pulling neither in favour nor against scientific realism. (shrink)

The present work is an attempt to break ground in mathematics proper, armed with the accepting view just described. Specifically, we shall examine various versions of antinomic set theory, in particular the axiom of choice, keeping the presentation as intuitive as possible, more in the manner of a nineteenth century paper than as a thoroughly formalized system. The reason for such a presentation is the conviction that at this point it should be the mathematics that eventually determines the logic, rather (...) than the other way around. (shrink)

Holobionts are symbiotic assemblages composed by a host plus its microbiome. The status of holobionts as individuals has recently been a subject of continuous controversy, which has given rise to two main positions: on the one hand, holobiont advocates argue that holobionts are biological individuals; on the other, holobiont detractors argue that they are just mere chimeras or ecological communities, but not individuals. Both parties in the dispute develop their arguments from the framework of the philosophy of biology, in terms (...) of what it takes for a “conglomerate” to be considered an interesting individual from a biological point of view. However, the debates about holobiont individuality have important ontological implications that have remained vaguely explored from a metaphysical framework. The purpose of this paper is to cover that gap by presenting a metaphysical approach to holobionts individuality. Drawing upon a conception of natural selection that puts the focus on the transgenerational recurrence of the traits and that supports the thesis that holobionts are units of selection, we argue that holobionts bear emergent traits and exert downward powers over the entities that compose them. In this vein, we argue, a reasonable argument can be made for conceiving holobionts as emergent biological individuals. (shrink)

The Spanish Jesuit Francisco Suarez was an eminent philosopher and theologian whose _Disputationes Metaphysicae_ was first published in Spain in 1597 and was widely studied throughout Europe during the seventeenth century. The _Disputationes Metaphysicae_ had a great influence on the development of early modern philosophy and on such well-known figures as Descartes and Leibniz. This is the first time that Disputations 17, 18, and 19 have been translated into English. The _Metaphysical Disputations_ provide an excellent philosophical introduction to the medieval (...) Aristotelian discussion of efficient causality. The work constitutes a synthesis of monumental proportions: problematic issues are lucidly delineated and the various arguments are laid out in depth. Disputations 17, 18, and 19 deal explicitly with such issues as the nature of causality, the types of efficient causes, the prerequisites for causal action, causal contingency, human free choice, and chance. (shrink)

A Richard Rorty se le considera hoy en día como uno de los filósofos más importantes de Norteamérica. Es posible que esta afirmación sea discutible; lo indiscutible es que, a juicio de los críticos, es el mejor escritor filosófico después de Bertrand Russell….

An English translation of the Second Disputation.

Scientific representation is a currently booming topic, both in analytical philosophy and in history and philosophy of science. The analytical inquiry attempts to come to terms with the relation between theory and world; while historians and philosophers of science aim to develop an account of the practice of model building in the sciences. This article provides a review of recent work within both traditions, and ultimately argues for a practice-based account of the means employed by scientists to effectively achieve representation (...) in the modelling sciences. (shrink)

This paper argues for a representational semantic conception of scientific theories, which respects the bare claim of any semantic view, namely that theories can be characterised as sets of models. RSC must be sharply distinguished from structural versions that assume a further identity of ‘models’ and ‘structures’, which we reject. The practice-turn in the recent philosophical literature suggests instead that modelling must be understood in a deflationary spirit, in terms of the diverse representational practices in the sciences. These insights are (...) applied to some mathematical models, thus showing that the mathematical sciences are not in principle counterexamples to RSC. (shrink)

This paper aims to offer a new argument in defence bacterial species pluralism. To do so, I shall first present the particular issues derived from the conflict between the non-theoretical understanding of species as units of classification and the theoretical comprehension of them as units of evolution. Secondly, I shall justify the necessity of the concept of species for the bacterial world, and show how medicine and endosymbiotic evolutionary theory make use of different concepts of bacterial species due to their (...) distinctive purposes. Finally, I shall show how my argument provides a new source of defence for bacterial pluralism. (shrink)

It is still a matter of controversy whether the Principle of the Common Cause (PCC) can be used as a basis for sound causal inference. It is thus to be expected that its application to quantum mechanics should be a correspondingly controversial issue. Indeed the early 90’s saw a flurry of papers addressing just this issue in connection with the EPR correlations. Yet, that debate does not seem to have caught up with the most recent literature on causal inference generally, (...) which has moved on to consider the virtues of a generalised PCC-inspired condition, the so-called Causal Markov Condition (CMC). In this paper we argue that the CMC is an appropriate benchmark for debating possible causal explanations of the EPR correlations. But we go on to take issue with some pronouncements on EPR by defenders of the CMC. (shrink)

Philippe Huneman has recently questioned the widespread application of mechanistic models of scientific explanation based on the existence of structural explanations, i.e. explanations that account for the phenomenon to be explained in virtue of the mathematical properties of the system where the phenomenon obtains, rather than in terms of the mechanisms that causally produce the phenomenon. Structural explanations are very diverse, including cases like explanations in terms of bowtie structures, in terms of the topological properties of the system, or in (...) terms of equilibrium. The role of mathematics in bowtie structured systems and in topologically constrained systems has recently been examined in different papers. However, the specific role that mathematical properties play in equilibrium explanations requires further examination, as different authors defend different interpretations, some of them closer to the new-mechanistic approach than to the structural model advocated by Huneman. In this paper, we cover this gap by investigating the explanatory role that mathematics play in Blaser and Kirschner’s nested equilibrium model of the stability of persistent long-term human-microbe associations. We argue that their model is explanatory because: i) it provides a mathematical structure in the form of a set of differential equations that together satisfy an ESS; ii) that the nested nature of the ESSs makes the explanation of host-microbe persistent associations robust to any perturbation; iii) that this is so because the properties of the ESS directly mirror the properties of the biological system in a non-causal way. The combination of these three theses make equilibrium explanations look more similar to structural explanations than to causal-mechanistic explanation. (shrink)

Scientific representation is a booming field nowadays within the philosophy of science, with many papers published regularly on the topic every year, and several yearly conferences and workshops held on related topics. Historically, the topic originates in two different strands in 20th-century philosophy of science. One strand begins in the 1950s, with philosophical interest in the nature of scientific theories. As the received or “syntactic” view gave way to a “semantic” or “structural” conception, representation progressively gained the center stage. Yet, (...) there is another, older, strand that links representation to fin de siècle modeling debates, particularly in the emerging Bildtheorie of Boltzmann and Hertz, and to the ensuing discussion among philosophers thereafter. Both strands feed into present-day philosophical work on scientific representation. There are a number of different orthogonal questions that philosophers ask regarding representation. One set of questions concerns the nature of the representational relation between theories or models, on the one hand, and the real-world systems they purportedly represent. Such questions lie at the more metaphysical and abstract end of the spectrum—and they are often addressed with the abstract tools of the analytical metaphysician. They constitute what we may refer to as the “analytical inquiry” into representation. On the other hand there are questions regarding the use that scientists put some representations to in practice—these are questions that are best addressed by means of some of the favorite tools of the philosopher of science, including descriptive analysis, illustration by means of case studies, induction, exemplification, inference from practice, etc., and are best referred to as the “practical inquiry” into representation. The notion of representation invoked in such inquiries may be “deflationary” or “substantive”—depending on whether it construes representation as a primitive notion, or as susceptible to further reduction or analysis in terms of something else. (shrink)

This paper defends the deflationary character of two recent views regarding scientific representation, namely RIG Hughes’ DDI model and the inferential conception. It is first argued that these views’ deflationism is akin to the homonymous position in discussions regarding the nature of truth. There, we are invited to consider the platitudes that the predicate “true” obeys at the level of practice, disregarding any deeper, or more substantive, account of its nature. More generally, for any concept X, a deflationary approach is (...) then defined in opposition to a substantive approach, where a substantive approach to X is an analysis of X in terms of some property P, or relation R, accounting for and explaining the standard use of X. It then becomes possible to characterize a deflationary view of scientific representation in three distinct senses, namely: a “no-theory” view, a “minimalist” view, and a “use-based” view – in line with three standard deflationary responses in the philosophical literature on truth. It is then argued that both the DDI model and the inferential conception may be suitably understood in any of these three different senses. The application of these deflationary ‘hermeneutics’ moreover yields significant improvements on the DDI model, which bring it closer to the inferential conception. It is finally argued that what these approaches have in common – the key to any deflationary account of scientific representation – is the denial that scientific representation may be ultimately reduced to any substantive explanatory property of sources, or targets, or their relations. (shrink)